S137 De novo psuedomonas aeruginosa colonisation is associated with increased acute rejection and bronchiolitis obliterans syndrome following lung transplantation
نویسندگان
چکیده
منابع مشابه
Bronchiolitis obliterans following lung transplantation.
Bronchiolitis obliterans syndrome (BOS) is the main and late chronic complication after lung transplantation. It remains a major impediment to long-term outcome. Unfortunately, the survival rate of lung transplant recipients lags behind that of other organ transplant recipients, and BOS accounts for more than 30% of all mortality after the third year following lung transplantation. Most recent ...
متن کاملDe novo donor HLA-specific antibodies predict development of bronchiolitis obliterans syndrome after lung transplantation.
BACKGROUND Bronchiolitis obliterans syndrome (BOS) is the major cause of late graft failure after lung transplantation. The objective was to determine whether de novo donor human leukocyte antigen (HLA)-specific antibodies (DSA) are associated with the development of BOS or patient survival. Data were analyzed from 188 lung transplant recipients with a follow-up period up to 8 years. METHODS ...
متن کاملBronchiolitis Obliterans Syndrome (BOS) Following Lung Transplant.
The main change seen with BOS is scarring of the small airways of transplanted lung(s). This scarring leads to narrowing of the airways, limiting airflow with loss of lung function. Early after the onset of BOS, a person may not have any symptoms, but will develop breathlessness and chronic cough as BOS gets worse. There are different stages of BOS based on lung function results. Some people de...
متن کاملPseudomonal airway colonisation: risk factor for bronchiolitis obliterans syndrome after lung transplantation?
Airway colonisation with Pseudomonads, especially Pseudomonas aeruginosa, is common in lung transplant (LTx) recipients. The current authors investigated whether pseudomonal colonisation affects the prevalence of bronchiolitis obliterans syndrome (BOS) after lung transplantation. In the present retrospective study, 92 double (SS)LTx recipients (26 cystic fibrosis (CF) and 66 non-CF patients), w...
متن کاملBronchiolitis Obliterans After Lung Transplantation
ing lung transplantation is 71%, and 46% of trans¬ plant recipients will survive at least 5 years.1 Al¬ though infections, medication-related adverse events, and malignancies remain important compli¬ cations, prolonged survival is limited predominantly by bronchiolitis obliterans (RO), a condition that was associated with transplantation more than a decade ago.25 Data suggest that at least 50% ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Thorax
سال: 2016
ISSN: 0040-6376,1468-3296
DOI: 10.1136/thoraxjnl-2016-209333.143